
Transmembrane Signaling in Development and Disease
In multicellular organisms, cell-cell communication is tightly controlled to ensure proper development and prevent diseases such as cancer. Our lab studies a key aspect of this process: how extracellular signals are transmitted across the membrane to the cell interior. We are tackling this problem from an interdisciplinary perspective, drawing on membrane biochemistry, cell biology, physiology, embryology, and a range of related approaches. A better understanding of transmembrane signaling will teach us how cellular identity is specified during development and in post-embryonic tissues, and help us to design better cancer therapies.
We're hiring! See our job ad here.
In multicellular organisms, cell-cell communication is tightly controlled to ensure proper development and prevent diseases such as cancer. Our lab studies a key aspect of this process: how extracellular signals are transmitted across the membrane to the cell interior. We are tackling this problem from an interdisciplinary perspective, drawing on membrane biochemistry, cell biology, physiology, embryology, and a range of related approaches. A better understanding of transmembrane signaling will teach us how cellular identity is specified during development and in post-embryonic tissues, and help us to design better cancer therapies.
We're hiring! See our job ad here.